First human-pig ‘chimera’ created in milestone study

Prospect of growing human organs for transplantation raised by creation of first ever embryos combining two large, distantly related species

Scientists have created a human-pig hybrid in a milestone study that raises the prospect of being able to grow human organs inside animals for use in transplants.

It marks the first time that embryos combining two large, distantly-related species have been produced. The creation of this so-called chimera – named after the cross-species beast of Greek mythology – has been hailed as a significant first step towards generating human hearts, livers and kidneys from scratch.

Related: Human-pig embryos Q&A: how would ‘chimeras’ make transplant organs?

Related: Human-pig chimeras and the history of xenotransplantation

Related: ‘Chimera’ monkeys created in lab by combining several embryos into one

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Prospect of growing human organs for transplantation raised by creation of first ever embryos combining two large, distantly related species

Scientists have created a human-pig hybrid in a milestone study that raises the prospect of being able to grow human organs inside animals for use in transplants.

It marks the first time that embryos combining two large, distantly-related species have been produced. The creation of this so-called chimera – named after the cross-species beast of Greek mythology – has been hailed as a significant first step towards generating human hearts, livers and kidneys from scratch.

Related: Human-pig embryos Q&A: how would ‘chimeras’ make transplant organs?

Related: Human-pig chimeras and the history of xenotransplantation

Related: ‘Chimera’ monkeys created in lab by combining several embryos into one

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U.S. government scientists go ‘rogue’ in defiance of Trump

(Reuters) – Rogue Twitter feeds voicing employee concerns at more than a dozen U.S. government agencies have been launched in defiance of what they say are President Donald Trump’s attempts to muzzle federal climate change research and other science.

(Reuters) – Rogue Twitter feeds voicing employee concerns at more than a dozen U.S. government agencies have been launched in defiance of what they say are President Donald Trump’s attempts to muzzle federal climate change research and other science.


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Nuclear ‘Doomsday Clock’ ticks closest to midnight in 64 years

WASHINGTON (Reuters) – Atomic scientists reset their symbolic “Doomsday Clock” to its closest time to midnight in 64 years on Thursday, saying the world was closer to catastrophe due to threats such as nuclear weapons, climate change and Donald Trump’s election as U.S. president.

WASHINGTON (Reuters) – Atomic scientists reset their symbolic “Doomsday Clock” to its closest time to midnight in 64 years on Thursday, saying the world was closer to catastrophe due to threats such as nuclear weapons, climate change and Donald Trump’s election as U.S. president.


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Barcelona thrash Real Sociedad to reach King’s Cup semis

BARCELONA (Reuters) – Lionel Messi and Luis Suarez were on target as holders Barcelona thrashed Real Sociedad 5-2 to reach the King’s Cup semi-finals for the seventh successive year with a 6-2 aggregate victory on Thursday.

BARCELONA (Reuters) – Lionel Messi and Luis Suarez were on target as holders Barcelona thrashed Real Sociedad 5-2 to reach the King’s Cup semi-finals for the seventh successive year with a 6-2 aggregate victory on Thursday.


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The worst forest fire in Chile’s history – in pictures

Chile is facing the worst forest fires it has ever seen, with more than 600 sq miles of land destroyed and thousands of people evacuated from their homes. The Chilean government has declared a state of emergency in several areas, as people try to save their homes, livestock and land

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Chile is facing the worst forest fires it has ever seen, with more than 600 sq miles of land destroyed and thousands of people evacuated from their homes. The Chilean government has declared a state of emergency in several areas, as people try to save their homes, livestock and land

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Trump: Meeting with Peña Nieto would have been ‘fruitless’ – video

President Trump says his meeting with Peña Nieto, the president of Mexico – now cancelled – would have been ‘fruitless’. Speaking at a meeting of congressional Republicans in Philadelphia on Thursday, Trump argued that this would remain the case until Mexico treats the US with the necessary respect

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President Trump says his meeting with Peña Nieto, the president of Mexico – now cancelled – would have been ‘fruitless’. Speaking at a meeting of congressional Republicans in Philadelphia on Thursday, Trump argued that this would remain the case until Mexico treats the US with the necessary respect

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How the world reacted to Trump’s inauguration as US president

Caution in China, sorrow and anger in Mexico, cork-popping in Moscow – here are some of the global responses to Friday’s power handover

Germany will need a new economic strategy geared toward Asia should the new US administration start a trade war with China, vice chancellor Sigmar Gabriel said, warning of a “rough ride” hours after Donald Trump was sworn in.

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Caution in China, sorrow and anger in Mexico, cork-popping in Moscow – here are some of the global responses to Friday’s power handover

Germany will need a new economic strategy geared toward Asia should the new US administration start a trade war with China, vice chancellor Sigmar Gabriel said, warning of a “rough ride” hours after Donald Trump was sworn in.

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US could face human rights crisis after Trump’s xenophobic immigration orders

Hidden among the promise of a wall and the withdrawal of funding to sanctuary cities is a much more insidious – and immediate – move to replace the ‘catch and release’ border policy with mandatory detention

Donald Trump is now effectively at war with undocumented migrants inside the US and those who attempt to cross the southern border without paperwork.

Advisers and analysts alike have long suggested that Trump ought to be taken “seriously but not literally”, but Wednesday’s two executive orders on immigration show that he is living up to the blustering rhetoric of the 2016 election trail.

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Hidden among the promise of a wall and the withdrawal of funding to sanctuary cities is a much more insidious – and immediate – move to replace the ‘catch and release’ border policy with mandatory detention

Donald Trump is now effectively at war with undocumented migrants inside the US and those who attempt to cross the southern border without paperwork.

Advisers and analysts alike have long suggested that Trump ought to be taken “seriously but not literally”, but Wednesday’s two executive orders on immigration show that he is living up to the blustering rhetoric of the 2016 election trail.

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The global fight for women’s rights, and a focus on gender inequality in Africa

The implications of the US’s reinstatement of the global gag rule, plus how African women are joining forces to improve their lot

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Women’s rights have topped the agenda over the past week. Our video explainer spells out the implications of the “global gag rule”, which has just been reinstated by the Trump administration. Campaigners say it will deny access to life-saving family planning and sexual and reproductive health services, and endanger the lives of millions of women around the world.

Across Africa, where one in five women already lacks access to contraception, feminists are forming a united front and championing women’s rights. Our latest podcast highlights those working to bring about gender equality across the continent.

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The implications of the US’s reinstatement of the global gag rule, plus how African women are joining forces to improve their lot

If you are reading this on the web and would prefer to get it in your inbox every two weeks, register for the email edition

Women’s rights have topped the agenda over the past week. Our video explainer spells out the implications of the “global gag rule”, which has just been reinstated by the Trump administration. Campaigners say it will deny access to life-saving family planning and sexual and reproductive health services, and endanger the lives of millions of women around the world.

Across Africa, where one in five women already lacks access to contraception, feminists are forming a united front and championing women’s rights. Our latest podcast highlights those working to bring about gender equality across the continent.

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‘Global gag rule’ on abortion puts $9bn in health aid at risk, activists say

Donald Trump’s executive order prompts fears for groups fighting Aids and Zika and working against child and maternal deaths

Billions of dollars in US aid to groups combating diseases worldwide could be at risk from Donald’s Trump’s “unprecedented and far-reaching” reversal of abortion-related policy, campaigners warned on Tuesday.

Trump signed an executive order on Monday reinstating the “global gag rule”, which bans funding for groups that offer abortions or abortion advocacy, even if they use their own funds to do so.

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Donald Trump’s executive order prompts fears for groups fighting Aids and Zika and working against child and maternal deaths

Billions of dollars in US aid to groups combating diseases worldwide could be at risk from Donald’s Trump’s “unprecedented and far-reaching” reversal of abortion-related policy, campaigners warned on Tuesday.

Trump signed an executive order on Monday reinstating the “global gag rule”, which bans funding for groups that offer abortions or abortion advocacy, even if they use their own funds to do so.

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Dutch respond to Trump’s ‘gag rule’ with international safe abortion fund

  • Up to 20 countries indicate support for fund to plug $600m funding gap
  • Netherlands minister: ‘It’s important to stand your ground’

Up to 20 countries have indicated support for the Netherlands’ plan to set up an international safe abortion fund to plug a $600m funding gap caused by Donald Trump’s reinstatement of the “global gag rule”, the Dutch international development minister, Lilianne Ploumen, said on Wednesday.

Ploumen took soundings from a number of her colleagues around the world on Tuesday evening after the Netherlands said it would act to mitigate the impact on hundreds of charities around the world.

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  • Up to 20 countries indicate support for fund to plug $600m funding gap
  • Netherlands minister: ‘It’s important to stand your ground’

Up to 20 countries have indicated support for the Netherlands’ plan to set up an international safe abortion fund to plug a $600m funding gap caused by Donald Trump’s reinstatement of the “global gag rule”, the Dutch international development minister, Lilianne Ploumen, said on Wednesday.

Ploumen took soundings from a number of her colleagues around the world on Tuesday evening after the Netherlands said it would act to mitigate the impact on hundreds of charities around the world.

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‘Global gag rule’ could have dire impact in Latin America, activists warn

Reinstatement of policy by Donald Trump could have ‘chilling impact’ in region that already has high rates of teenage pregnancy and maternal mortality

Donald Trump’s reversal of abortion-related aid policy will have a “chilling impact” on Latin America, say family-planning campaigners in a region that already has some of the world’s highest rates of teenage pregnancy and maternal mortality.

The so-called global gag rule, which was signed into effect by the new US president on Monday, withholds USAid funding from any organisation that offers abortion services or information.

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Reinstatement of policy by Donald Trump could have ‘chilling impact’ in region that already has high rates of teenage pregnancy and maternal mortality

Donald Trump’s reversal of abortion-related aid policy will have a “chilling impact” on Latin America, say family-planning campaigners in a region that already has some of the world’s highest rates of teenage pregnancy and maternal mortality.

The so-called global gag rule, which was signed into effect by the new US president on Monday, withholds USAid funding from any organisation that offers abortion services or information.

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‘Global gag rule’ jeopardises future of Asia health initiatives, campaigners say

Funding for programmes from sanitation to nutrition will be subject to Trump’s far-reaching order, with huge implications for family planning providers

Women’s health advocates across Asia have said Donald Trump’s decision to reinstate and beef up the “global gag rule” will result in hundreds of thousands of unwanted pregnancies and imperil programmes aimed at improving sanitation, treating Aids and protecting LGBT activists.

Health providers and advocacy groups in Delhi, Phnom Penh, Jakarta and beyond have been holding emergency meetings since Tuesday’s announcement that US aid funding was now contingent on organisations abandoning their abortion advocacy work, services or information.

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Funding for programmes from sanitation to nutrition will be subject to Trump’s far-reaching order, with huge implications for family planning providers

Women’s health advocates across Asia have said Donald Trump’s decision to reinstate and beef up the “global gag rule” will result in hundreds of thousands of unwanted pregnancies and imperil programmes aimed at improving sanitation, treating Aids and protecting LGBT activists.

Health providers and advocacy groups in Delhi, Phnom Penh, Jakarta and beyond have been holding emergency meetings since Tuesday’s announcement that US aid funding was now contingent on organisations abandoning their abortion advocacy work, services or information.

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‘I want to kill these dogs’: question of whether to cull strays divides Yangon

Myanmar’s commercial capital is overrun with an estimated 120,000 stray dogs, which attack children and carry the threat of rabies. Mass culling was recently stopped but spay, neuter and vaccinate programmes have yet to start

Zu May Naing was playing with her brother outside their house in Bago Region, close to Myanmar’s commercial capital of Yangon, last month when a pack of stray dogs rounded on the 18-month-old.

Her mother, San Thar Myint, found her lying prone on the ground, bleeding and in shock. “Her temperature was over 100 [degrees fahrenheit] before they got to the operation room,” she says.

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Myanmar’s commercial capital is overrun with an estimated 120,000 stray dogs, which attack children and carry the threat of rabies. Mass culling was recently stopped but spay, neuter and vaccinate programmes have yet to start

Zu May Naing was playing with her brother outside their house in Bago Region, close to Myanmar’s commercial capital of Yangon, last month when a pack of stray dogs rounded on the 18-month-old.

Her mother, San Thar Myint, found her lying prone on the ground, bleeding and in shock. “Her temperature was over 100 [degrees fahrenheit] before they got to the operation room,” she says.

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Will New York get a Brexit boost to cancel out feared ‘Trump slump’?

While European cities led by Paris and Frankfurt wage campaigns for London’s financial business, some experts predict New York could benefit most of all from the fallout of Brexit on the UK capital

New York and London function as two prongs of one global economy. Banks and other financial companies headquartered in New York usually have their second biggest offices in the British capital, and vice versa.

For years, that’s made economic sense. For London-based companies, New York provides an unparalleled density of financial firms, a regulatory framework in which to do business, and access to non-European markets. London provides much of the same for New York-based companies who need access to European markets.

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While European cities led by Paris and Frankfurt wage campaigns for London’s financial business, some experts predict New York could benefit most of all from the fallout of Brexit on the UK capital

New York and London function as two prongs of one global economy. Banks and other financial companies headquartered in New York usually have their second biggest offices in the British capital, and vice versa.

For years, that’s made economic sense. For London-based companies, New York provides an unparalleled density of financial firms, a regulatory framework in which to do business, and access to non-European markets. London provides much of the same for New York-based companies who need access to European markets.

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The future of the US-Mexican border: inside the ‘split city’ of El Paso-Juárez

One has been called the world’s most violent city. The other, the safest in its nation. Schoolchildren commute daily between the ‘binational’ cities of Juárez, Mexico and El Paso, Texas – but with Trump in office, will border divisions grow?

Unlike most teenagers, Ashley Delgado starts her school day by crossing an international border. She gets up at 5am so her mother Dora can drive through Juárez’s dense traffic to the Paso del Norte bridge, where she follows the caged pathway between Mexico and the United States by foot. Clearing customs takes on average half an hour, but often it’s double that – depending on the line and the guards’ moods.

“Sometimes they put people in a little room for investigation and start to ask questions,” says the 14-year-old as her mum picks her up from the Mexican side at the end of a school day. “Where are you from? What are you bringing? What are you going to do in the US? It’s never happened to me, but to some of my friends it happens every three days.

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One has been called the world’s most violent city. The other, the safest in its nation. Schoolchildren commute daily between the ‘binational’ cities of Juárez, Mexico and El Paso, Texas – but with Trump in office, will border divisions grow?

Unlike most teenagers, Ashley Delgado starts her school day by crossing an international border. She gets up at 5am so her mother Dora can drive through Juárez’s dense traffic to the Paso del Norte bridge, where she follows the caged pathway between Mexico and the United States by foot. Clearing customs takes on average half an hour, but often it’s double that – depending on the line and the guards’ moods.

“Sometimes they put people in a little room for investigation and start to ask questions,” says the 14-year-old as her mum picks her up from the Mexican side at the end of a school day. “Where are you from? What are you bringing? What are you going to do in the US? It’s never happened to me, but to some of my friends it happens every three days.

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Raúl Castro: Cuba won’t compromise sovereignty to normalize US relations

President said Cuba hopes to continue to repair relations but made it clear that Trump administration should not expect concessions affecting independence

Raúl Castro has said Cuba hopes to continue to normalize relations with the United States but made it clear that the Trump administration should not expect concessions affecting the country’s sovereignty.

Before taking office, Donald Trump threatened to torpedo the still fragile detente between the former cold war foes unless a “better deal” could be struck, without providing details. His aides have said current policy is under review.

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President said Cuba hopes to continue to repair relations but made it clear that Trump administration should not expect concessions affecting independence

Raúl Castro has said Cuba hopes to continue to normalize relations with the United States but made it clear that the Trump administration should not expect concessions affecting the country’s sovereignty.

Before taking office, Donald Trump threatened to torpedo the still fragile detente between the former cold war foes unless a “better deal” could be struck, without providing details. His aides have said current policy is under review.

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Mexico’s president ‘will not pay for any wall’ – but may still visit Trump

Enrique Peña Nieto repeats his refusal to fund border wall but leaves open the question of contentious 31 January trip to meet new US president

Mexico’s president has once again declared that “Mexico will not pay for any wall” but stopped short of cancelling a visit to Washington after Donald Trump signed executive orders that include building the border barrier.

Enrique Peña Nieto reiterated that Mexico would not put a single peso towards the new US president’s signature project. In a televised address he said: “I regret and reject the decision of the US to build the wall.”

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Enrique Peña Nieto repeats his refusal to fund border wall but leaves open the question of contentious 31 January trip to meet new US president

Mexico’s president has once again declared that “Mexico will not pay for any wall” but stopped short of cancelling a visit to Washington after Donald Trump signed executive orders that include building the border barrier.

Enrique Peña Nieto reiterated that Mexico would not put a single peso towards the new US president’s signature project. In a televised address he said: “I regret and reject the decision of the US to build the wall.”

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Mexican president ‘demands respect’ and rejects US border wall – video

President Enrique Peña Nieto says he rejects the decision by the US president, Donald Trump, to build a border wall and repeats that his country will not pay for its construction. In a recorded address televised nationally, Mexico’s leader says: ‘I am saddened and am against the decision by the United States to continue with the construction of a wall.’ He adds: ‘Mexico offers and demands respect’

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President Enrique Peña Nieto says he rejects the decision by the US president, Donald Trump, to build a border wall and repeats that his country will not pay for its construction. In a recorded address televised nationally, Mexico’s leader says: ‘I am saddened and am against the decision by the United States to continue with the construction of a wall.’ He adds: ‘Mexico offers and demands respect’

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Austria’s new president calls for a tolerant nation and united Europe

In his first speech since beating rightwing rival Norbert Hofer in election, Alexander Van der Bellen rejects nationalism

Austria’s new president has called for a tolerant and diverse nation, free of ideological and racial hatred, in an inauguration speech on Thursday that embraced the ideal of a united Europe.

Alexander Van der Bellen outlined a markedly different vision from that offered during campaigning by his rightwing rival Norbert Hofer, the populist he defeated last month after an unprecedented repeat vote.

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In his first speech since beating rightwing rival Norbert Hofer in election, Alexander Van der Bellen rejects nationalism

Austria’s new president has called for a tolerant and diverse nation, free of ideological and racial hatred, in an inauguration speech on Thursday that embraced the ideal of a united Europe.

Alexander Van der Bellen outlined a markedly different vision from that offered during campaigning by his rightwing rival Norbert Hofer, the populist he defeated last month after an unprecedented repeat vote.

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Trump pressured parks chief for photos to prove ‘media lied’ about inauguration crowd – report

Post story came as reports suggested Trump had been obsessed with stories that accurately said inauguration had noticeably smaller crowd than Obama’s in 2009

Donald Trump ordered the National Park Service director to produce additional photographs of his inauguration crowds, believing the images “might prove that the media had lied” about the size of the audience, according to the Washington Post.

In a Saturday phone call, the president told Michael Reynolds, acting NPS director, that he wanted to see more photos because he thought they could show that the attendance at his Friday swearing-in ceremonies at the National Mall was above average, three sources with knowledge of the conversation told the Post.

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Post story came as reports suggested Trump had been obsessed with stories that accurately said inauguration had noticeably smaller crowd than Obama’s in 2009

Donald Trump ordered the National Park Service director to produce additional photographs of his inauguration crowds, believing the images “might prove that the media had lied” about the size of the audience, according to the Washington Post.

In a Saturday phone call, the president told Michael Reynolds, acting NPS director, that he wanted to see more photos because he thought they could show that the attendance at his Friday swearing-in ceremonies at the National Mall was above average, three sources with knowledge of the conversation told the Post.

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Cold-call investment scam accused stole $3.2m from victims, say police

Tomas Anthony Novak, 51, was granted bail after he was extradited from South Australia to the Gold Coast

A man extradited from South Australia to Queensland on multiple fraud charges is personally responsible for stealing $3.2m from victims, police say.

Tomas Anthony Novak, 51, was granted bail at Southport magistrates court on Friday after being extradited to the Gold Coast.

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Tomas Anthony Novak, 51, was granted bail after he was extradited from South Australia to the Gold Coast

A man extradited from South Australia to Queensland on multiple fraud charges is personally responsible for stealing $3.2m from victims, police say.

Tomas Anthony Novak, 51, was granted bail at Southport magistrates court on Friday after being extradited to the Gold Coast.

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Donald Trump’s plan for China relations is to be unpredictable, adviser says

Since his election, Trump has confused Beijing with comments on South China Sea, Taiwan and the yuan

Donald Trump’s game plan for relations with China is to use unpredictability as a means of wrong-footing the country’s Communist party leaders and extracting economic concessions, a prominent adviser has said.

Since his election, Trump and his team have repeatedly discombobulated the Chinese government with a series of interventions on sensitive issues such as the South China Sea, US relations with Taiwan and China’s alleged manipulation of its currency, the yuan.

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Since his election, Trump has confused Beijing with comments on South China Sea, Taiwan and the yuan

Donald Trump’s game plan for relations with China is to use unpredictability as a means of wrong-footing the country’s Communist party leaders and extracting economic concessions, a prominent adviser has said.

Since his election, Trump and his team have repeatedly discombobulated the Chinese government with a series of interventions on sensitive issues such as the South China Sea, US relations with Taiwan and China’s alleged manipulation of its currency, the yuan.

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Mike Pence: Trump administration planning ‘full evaluation’ of voter fraud

In audio obtained by the Guardian, vice-president described investigation amid Trump’s unfounded claims that millions voted illegally in 2016 election

Vice-President Mike Pence said that the Trump administration will “initiate a full evaluation of voting rolls in the country and the overall integrity of our voting system in the wake of this past election”, according to audio obtained by the Guardian.

Related: Donald Trump still holds baseless belief that millions voted illegally

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In audio obtained by the Guardian, vice-president described investigation amid Trump’s unfounded claims that millions voted illegally in 2016 election

Vice-President Mike Pence said that the Trump administration will “initiate a full evaluation of voting rolls in the country and the overall integrity of our voting system in the wake of this past election”, according to audio obtained by the Guardian.

Related: Donald Trump still holds baseless belief that millions voted illegally

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Will Trump return USA to dark days of ‘war on terror’ black sites?

President appears to believe ‘torture works’ – raising prospect of reviving techniques the CIA had moved away from

One of the common features of the multiple conflicts that followed the 9/11 attacks on the US was the use of secret prisons. Islamic extremists used them – most notably Abu Musab al-Zarqawi, the leader of al-Qaida in Iraq – and so did a range of states in the Middle East, south Asia and beyond. Many had been doing so for many years.

But one of the most enthusiastic users of secret prisons – and torture – in the years following 9/11 was the USA. Its sites eventually numbered more than 100, it is believed, spanning half the world. It is this network of “black sites” that Donald Trump appears to be considering reviving.

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President appears to believe ‘torture works’ – raising prospect of reviving techniques the CIA had moved away from

One of the common features of the multiple conflicts that followed the 9/11 attacks on the US was the use of secret prisons. Islamic extremists used them – most notably Abu Musab al-Zarqawi, the leader of al-Qaida in Iraq – and so did a range of states in the Middle East, south Asia and beyond. Many had been doing so for many years.

But one of the most enthusiastic users of secret prisons – and torture – in the years following 9/11 was the USA. Its sites eventually numbered more than 100, it is believed, spanning half the world. It is this network of “black sites” that Donald Trump appears to be considering reviving.

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Romania’s corruption fight is a smokescreen to weaken its democracy

Turning a blind eye to this abuse of power risks encouraging other European nations to follow its example

The recent rise of the populist right in Hungary and Poland has raised the alarm about the future of democracy in Europe, as constitutional safeguards, media pluralism and civil society come under sustained attack.

But there is another threat hiding in plain sight: the abuse of anti-corruption laws in Romania, a country often lauded as an example of successful reform in central and eastern Europe.

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Turning a blind eye to this abuse of power risks encouraging other European nations to follow its example

The recent rise of the populist right in Hungary and Poland has raised the alarm about the future of democracy in Europe, as constitutional safeguards, media pluralism and civil society come under sustained attack.

But there is another threat hiding in plain sight: the abuse of anti-corruption laws in Romania, a country often lauded as an example of successful reform in central and eastern Europe.

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‘My neighbour murdered nearly all of my family, but now we are friends’

Thanks to a pioneering reconciliation project survivors and perpetrators of the Rwandan genocide now live side by side

In a leafy, quiet district less than an hour’s drive from Rwanda’s capital, the calmness of the community of Mbyo belies the dark and traumatic past of its inhabitants.

Related: My journey back to Rwanda: confronting the ghosts of the genocide 21 years later

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Thanks to a pioneering reconciliation project survivors and perpetrators of the Rwandan genocide now live side by side

In a leafy, quiet district less than an hour’s drive from Rwanda’s capital, the calmness of the community of Mbyo belies the dark and traumatic past of its inhabitants.

Related: My journey back to Rwanda: confronting the ghosts of the genocide 21 years later

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Ebola, war … but just two psychiatrists to deal with a nation’s trauma

Overwhelmed counsellors and medical staff in Sierra Leone must contend with suspicion and a collapse in funding

The history of Africa’s oldest psychiatric hospital is written on the walls of its isolation units, desperate messages chiselled into the woodwork like scars. “I came here for I don’t have any money,” reads one note in a corner of the room. “People want me to run from my father’s house,” reads another. “You go nowhere,” announces a third. “Stay out.”

Since the hospital opened in the early 19th century, most Sierra Leoneans have aspired to do exactly that, avoiding this imposing building perched high on a hill above the capital, Freetown.

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Overwhelmed counsellors and medical staff in Sierra Leone must contend with suspicion and a collapse in funding

The history of Africa’s oldest psychiatric hospital is written on the walls of its isolation units, desperate messages chiselled into the woodwork like scars. “I came here for I don’t have any money,” reads one note in a corner of the room. “People want me to run from my father’s house,” reads another. “You go nowhere,” announces a third. “Stay out.”

Since the hospital opened in the early 19th century, most Sierra Leoneans have aspired to do exactly that, avoiding this imposing building perched high on a hill above the capital, Freetown.

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‘Opposites attract’: Theresa May signals strong relationship with Trump

UK prime minister launches charm offensive on arrival in Philadelphia, suggesting she will get on well with US president

Theresa May has said she believed she could a forge a strong personal relationship with Donald Trump, arguing that “sometimes, opposites attract”, as she set out how post-Brexit Britain could work with his country to shape the world.

Related: Theresa May opens Trump visit by attacking past foreign policy failures

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UK prime minister launches charm offensive on arrival in Philadelphia, suggesting she will get on well with US president

Theresa May has said she believed she could a forge a strong personal relationship with Donald Trump, arguing that “sometimes, opposites attract”, as she set out how post-Brexit Britain could work with his country to shape the world.

Related: Theresa May opens Trump visit by attacking past foreign policy failures

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Victorian opposition leader’s comments ‘unfortunate’, says South Africa’s ANC

Matthew Guy said Melbourne could become ‘the Johannesburg of the South Pacific’ over a perceived increase in crime

The ruling party of South Africa has criticised the Victorian opposition leader, Matthew Guy, for saying Melbourne could become “the Johannesburg of the South Pacific” over a perceived increase in crime.

The African National Congress (ANC) released a statement saying Guy’s comments were “unfortunate” and “seek to portray South Africa in a negative manner”.

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Matthew Guy said Melbourne could become ‘the Johannesburg of the South Pacific’ over a perceived increase in crime

The ruling party of South Africa has criticised the Victorian opposition leader, Matthew Guy, for saying Melbourne could become “the Johannesburg of the South Pacific” over a perceived increase in crime.

The African National Congress (ANC) released a statement saying Guy’s comments were “unfortunate” and “seek to portray South Africa in a negative manner”.

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Chile battles devastating wildfires: ‘We have never seen anything on this scale’

The world’s largest firefighting aircraft has flown in from the US, alongside help from France, Peru and Mexico, as fires continue to ravage Chilean lands

The world’s biggest aerial firefighting aircraft has joined beleaguered firefighters in Chile as they battle the worst wildfires in the country’s recent history.

More than 90 blazes have scorched 180,000 hectares, razed hundreds of homes, turned village schools to ashes and destroyed cattle herds and vineyards.

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The world’s largest firefighting aircraft has flown in from the US, alongside help from France, Peru and Mexico, as fires continue to ravage Chilean lands

The world’s biggest aerial firefighting aircraft has joined beleaguered firefighters in Chile as they battle the worst wildfires in the country’s recent history.

More than 90 blazes have scorched 180,000 hectares, razed hundreds of homes, turned village schools to ashes and destroyed cattle herds and vineyards.

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Doctors save Canadian woman’s life by removing her lungs for six days

Melissa Benoit’s terminal lung infection called for risky and unprecedented procedure while she waited for double transplant at Toronto hospital

In what is believed to be the first procedure of its kind in the world, doctors in Canada have saved a young mother’s life by resorting to a radical solution – they removed her lungs for six days while she waited for a transplant.

In April, Melissa Benoit arrived at a Toronto hospital with a severe lung infection. Doctors soon realised that Benoit, who had been born with cystic fibrosis, had just hours to live, leading them to consider the unprecedented approach.

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Melissa Benoit’s terminal lung infection called for risky and unprecedented procedure while she waited for double transplant at Toronto hospital

In what is believed to be the first procedure of its kind in the world, doctors in Canada have saved a young mother’s life by resorting to a radical solution – they removed her lungs for six days while she waited for a transplant.

In April, Melissa Benoit arrived at a Toronto hospital with a severe lung infection. Doctors soon realised that Benoit, who had been born with cystic fibrosis, had just hours to live, leading them to consider the unprecedented approach.

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May’s meeting with Trump: a collision of contrasting world views

The PM’s visit could be seen as a diplomatic coup, but her vision of a free-trading Britain could crash into ‘America First’

Theresa May travels to the US on Thursday to try to forge a personal and political relationship with the least predictable and, in European terms, most unpopular US president in modern times.

For all the British diplomatic pleasure that their prime minister is once again the first foreign leader through the door of a newly elected president, as John Major managed in the case of Bill Clinton in 1993, there will be wariness in Downing Street. For the first time since the second world war, the US appears to have a president who displays indifference to supporting his allies or shoring up an alliance framework.

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The PM’s visit could be seen as a diplomatic coup, but her vision of a free-trading Britain could crash into ‘America First’

Theresa May travels to the US on Thursday to try to forge a personal and political relationship with the least predictable and, in European terms, most unpopular US president in modern times.

For all the British diplomatic pleasure that their prime minister is once again the first foreign leader through the door of a newly elected president, as John Major managed in the case of Bill Clinton in 1993, there will be wariness in Downing Street. For the first time since the second world war, the US appears to have a president who displays indifference to supporting his allies or shoring up an alliance framework.

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Makhado mine: flashpoint for tensions over South Africa’s pro-coal policies

A campaign by locals and farming businesses to halt a large opencast mine highlights a far wider conflict over South Africa’s continued addiction to coal

On the horizon are the mountains, verdant rainforest on their well-watered, shaded southern slopes and arid scrub on the dry reverse slopes. Then there is the plain, studded with baobab trees and outcrops. Finally there is the river Limpopo. Beyond is another country: troubled, restive Zimbabwe.

But here in the far north-east of South Africa, there is tension, too. In the Soutpansberg range and on the flat lands beyond, an improbable coalition of local farmers, villagers, big agricultural businessmen and activists are fighting to halt the development of a large opencast mine which, they say, would cause massive harm to the region.

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A campaign by locals and farming businesses to halt a large opencast mine highlights a far wider conflict over South Africa’s continued addiction to coal

On the horizon are the mountains, verdant rainforest on their well-watered, shaded southern slopes and arid scrub on the dry reverse slopes. Then there is the plain, studded with baobab trees and outcrops. Finally there is the river Limpopo. Beyond is another country: troubled, restive Zimbabwe.

But here in the far north-east of South Africa, there is tension, too. In the Soutpansberg range and on the flat lands beyond, an improbable coalition of local farmers, villagers, big agricultural businessmen and activists are fighting to halt the development of a large opencast mine which, they say, would cause massive harm to the region.

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Brazil’s former richest man sought by police in vast corruption inquiry

Eike Batista, businessman who made and lost billion-dollar fortune, accused of paying bribes to Rio de Janeiro state governor

Brazilian police have issued an arrest warrant for a businessman famous for amassing and then losing a multibillion-dollar fortune, the latest person caught up in a wide-ranging corruption investigation roiling Latin America’s largest country.

Federal police were working with Interpol to locate Eike Batista, who may be in New York. Batista’s lawyer Fernando Martins told the G1 news portal that his client was travelling and would surrender to police.

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Eike Batista, businessman who made and lost billion-dollar fortune, accused of paying bribes to Rio de Janeiro state governor

Brazilian police have issued an arrest warrant for a businessman famous for amassing and then losing a multibillion-dollar fortune, the latest person caught up in a wide-ranging corruption investigation roiling Latin America’s largest country.

Federal police were working with Interpol to locate Eike Batista, who may be in New York. Batista’s lawyer Fernando Martins told the G1 news portal that his client was travelling and would surrender to police.

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Lonmin: we can’t afford to house Marikana massacre families

Amid protests on 5th anniversary of deaths platinum mine owner tells AGM rockbottom metal prices means housebuilding has been slow

Platinum miner Lonmin has come under attack over its record on conditions for its workers, nearly five years after dozens of people were killed in violence at its Marikana mine in South Africa.

Speaking as protesters displayed placards bearing the names of the dead, the chief executive, Ben Magara, told shareholders at the group’s annual meeting that progress on building homes for 33,000 staff had been “slower than we would have liked”.

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Amid protests on 5th anniversary of deaths platinum mine owner tells AGM rockbottom metal prices means housebuilding has been slow

Platinum miner Lonmin has come under attack over its record on conditions for its workers, nearly five years after dozens of people were killed in violence at its Marikana mine in South Africa.

Speaking as protesters displayed placards bearing the names of the dead, the chief executive, Ben Magara, told shareholders at the group’s annual meeting that progress on building homes for 33,000 staff had been “slower than we would have liked”.

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Protesters gather in New York as fear grows over Trump’s immigration plans

Thousands gathered after news broke that Trump intended to sign executive order to temporarily halt US entry for citizens of Muslim-majority countries

Thousands of New Yorkers gathered in the city’s Washington Square Park on Wednesday night to protest the expected enforcement of a ban on people from several Muslim-majority countries entering the United States.

Related: ‘Sanctuary cities’ endangered by Trump order threatening to cut federal funds

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Thousands gathered after news broke that Trump intended to sign executive order to temporarily halt US entry for citizens of Muslim-majority countries

Thousands of New Yorkers gathered in the city’s Washington Square Park on Wednesday night to protest the expected enforcement of a ban on people from several Muslim-majority countries entering the United States.

Related: ‘Sanctuary cities’ endangered by Trump order threatening to cut federal funds

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Mark Zuckerberg ‘reconsiders’ forcing Hawaiians to sell him their land

Facebook CEO makes statement after backlash over ‘quiet title actions’ to secure parcels belonging to native owners within his $100m seafront property

Mark Zuckerberg has said he is reconsidering whether to seek the forced sale of tracts of land belonging to native Hawaiians in a large estate he bought on the island of Kauai, after facing a wave of criticism.

The Facebook CEO filed a series of lawsuits, known as quiet title actions, against hundreds of Hawaiians who may own small parcels of land within the boundaries of his seafront property on Kauai. The quiet title system is used to establish ownership of land where inheritance has occurred over generations and lacks formal documentation. It can result in owners being forced to sell their land at auction and, in some cases, pay the legal fees of the plaintiff.

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Facebook CEO makes statement after backlash over ‘quiet title actions’ to secure parcels belonging to native owners within his $100m seafront property

Mark Zuckerberg has said he is reconsidering whether to seek the forced sale of tracts of land belonging to native Hawaiians in a large estate he bought on the island of Kauai, after facing a wave of criticism.

The Facebook CEO filed a series of lawsuits, known as quiet title actions, against hundreds of Hawaiians who may own small parcels of land within the boundaries of his seafront property on Kauai. The quiet title system is used to establish ownership of land where inheritance has occurred over generations and lacks formal documentation. It can result in owners being forced to sell their land at auction and, in some cases, pay the legal fees of the plaintiff.

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Turkey and Russia skeptical of Trump’s plan to create safe havens in Syria

US president’s proposal met with caution from Russian and Turkish officials over northern safe zones as others fear possible intention to keep refugees out of US

Donald Trump’s proposal to set up safe havens in northern Syria has been met with caution by his allies and skepticism by others who fear the plan is aimed more at keeping refugees out of the US than providing for humanitarian needs.

Turkey and Russia, on whom such a plan would heavily depend, on Thursday said they had not been consulted, hours after the US president pledged to “absolutely do safe zones in Syria for the people”. Moscow said it was important not to “exacerbate the situation”, while Ankara said a safe zone had already been set up under its auspices.

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US president’s proposal met with caution from Russian and Turkish officials over northern safe zones as others fear possible intention to keep refugees out of US

Donald Trump’s proposal to set up safe havens in northern Syria has been met with caution by his allies and skepticism by others who fear the plan is aimed more at keeping refugees out of the US than providing for humanitarian needs.

Turkey and Russia, on whom such a plan would heavily depend, on Thursday said they had not been consulted, hours after the US president pledged to “absolutely do safe zones in Syria for the people”. Moscow said it was important not to “exacerbate the situation”, while Ankara said a safe zone had already been set up under its auspices.

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Italian authorities look into ‘racist’ video of man drowning in Venice

Onlookers allegedly yelled insults and abuse at Pateh Sabally, a 22-year-old Gambian, as he drowned in Grand Canal

Italian magistrates have launched an investigation after a video was posted online showing an African man drowning in Venice’s Grand Canal as onlookers watched and shouted racial abuse from nearby boats, local media said.

The recording shown on various news websites appeared to pick up some bystanders yelling at the flailing man. “He is stupid. He wants to die,” one person says. Another person allegedly shouts: “Go on, go back home.”

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Onlookers allegedly yelled insults and abuse at Pateh Sabally, a 22-year-old Gambian, as he drowned in Grand Canal

Italian magistrates have launched an investigation after a video was posted online showing an African man drowning in Venice’s Grand Canal as onlookers watched and shouted racial abuse from nearby boats, local media said.

The recording shown on various news websites appeared to pick up some bystanders yelling at the flailing man. “He is stupid. He wants to die,” one person says. Another person allegedly shouts: “Go on, go back home.”

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